Article
Acidic-phospholipid deficiency represses the flagellar master operon through a novel regulatory region in Escherichia coli.
Bioscience, biotechnology, and biochemistry - 1 Dec 1994
Kitamura E, Nakayama Y, Matsuzaki H, Matsumoto K, Shibuya I
Abstract excerpt
The Escherichia coli pgsA3 mutation, which causes acidic-phospholipid deficiency, was found to repress the flagellar master operon, as assessed by the beta-galactosidase activities of flhD-lacZ fusions. This explained the impairment of flagellar formation and motility by the mutation. A series of deletion analysis indicated that a 40-bp region, at the 5' end of the flhD locus examined, was responsible for the...
Topics
- Bacterial Proteins
- Base Sequence
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Molecular Sequence Data
- Mutation
- Operon
- Phospholipids
- Regulatory Sequences, Nucleic Acid