A susceptibility gene for alveolar lung tumors in the mouse maps between Hsp70.3 and G7 within the H2 complex.

doi:10.1007/BF00182320

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Article

A susceptibility gene for alveolar lung tumors in the mouse maps between Hsp70.3 and G7 within the H2 complex.

Immunogenetics - 1 Jan 1995

Fijneman R J, Oomen L C, Snoek M, Demant P

Abstract excerpt

Lung tumor susceptibility (LTS) in the mouse is influenced by multiple loci within the H2 complex. We compared the LTS of two H2 congenic strains with intra H2 recombinations, B10.A(1R) and B10.A(2R), whose genetic difference has been reduced to a region of approximately 50 kilobases within the C...

Topics

Animals
Chromosome Mapping
Ethylnitrosourea
Female
Genetic Predisposition to Disease
H-2 Antigens
Lung Neoplasms
Male
Mice
Mice, Inbred C57BL
Pulmonary Alveoli
Recombination, Genetic

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