Article
Type-IV collagenase and tissue inhibitor of metalloproteinase in ovarian cancer tissues.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics - 1 Sept 1994
Takemura M, Azuma C, Kimura T, Kanai T, Saji F, Tanizawa O
Abstract excerpt
OBJECTIVE: We examined the specific expression of gelatinase/type-IV collagenase and tissue inhibitor of metalloproteinase (TIMP) in clinical ovarian cancer tissue. METHODS: Molecular weight-specific gelatinase/type-IV collagenase activity was examined by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis in which substrate was included (zymography). The expression of TIMP mRNA was examined by...
Topics
- Adenocarcinoma, Clear Cell
- Aged
- Blotting, Northern
- Carcinoma, Endometrioid
- Case-Control Studies
- Collagenases
- Culture Techniques
- Cystadenocarcinoma
- Electrophoresis, Polyacrylamide Gel
- Female
