Article
MMPs in ovarian cancer as therapeutic targets.
Anti-cancer agents in medicinal chemistry - 1 Sept 2012
Karam Amer, Dorigo Oliver
Abstract excerpt
In the United States, about 22,000 women will be diagnosed with ovarian cancer in 2011, and an estimated 14,000 patients will succumb to the disease. Surgery and chemotherapy present the main treatment modalities, but despite the development of novel therapies, the overall 5 years survival for ovarian cancer patients with advanced disease at diagnosis remains at only about 30%. Novel therapeutic strategies are...
Topics
- Antineoplastic Agents
- Clinical Trials as Topic
- Female
- Humans
- Matrix Metalloproteinase Inhibitors
- Matrix Metalloproteinases
- Molecular Targeted Therapy
- Ovarian Neoplasms
- Ovary
- Peptidomimetics
- Polymorphism, Single Nucleotide
- Tetracyclines
