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Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas

1 Aug 1995

Abstract excerpt

The gene expression of five matrix metalloproteinases (MMPs) and two tissue inhibitors of metalloproteinases (TIMPs) was studied in human gliomas in vivo and in vitro to evaluate their roles in glioma invasion. Simultaneous expression of one to four MMP genes and two TIMP genes was found in 17 surgical glioma specimens, and one MMP (gelatinase A) gene and two TIMP genes were simultaneously expressed in tissue of...

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Identifiers

PMID: 7616276
DOI: 10.3171/jns.1995.83.2.0298

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