Article
The behavior of matrix metalloproteinases and their inhibitors in colorectal cancer.
International journal of molecular sciences - 16 Oct 2012
Herszényi László, Hritz István, Lakatos Gábor, Varga Mária Zsófia, Tulassay Zsolt
Abstract excerpt
Matrix metalloproteinases (MMPs) play an important role in the degradation of extracellular matrix components crucial for tumor growth, invasion and metastasis. MMPs are controlled by natural inhibitors called tissue inhibitors of metalloproteinases (TIMPs). We and others have demonstrated that MMPs and TIMPs are especially important in the process of tumor invasion, progression and the metastasis of colorectal...
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