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Article

Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2004

Curran Stephanie, Dundas Sinclair R, Buxton Jenny, Leeman Matthew F, Ramsay Robin, Murray Graeme I

Abstract excerpt

PURPOSE: The matrix metalloproteinases (MMPs) are a family of proteolytic enzymes involved in tumor invasion; several individual members of which have been implicated in tumor prognosis. These enzymes and their physiologic inhibitors, the tissue inhibitors of matrix metalloproteinases (TIMPs), act in a coordinated manner to form an integrated system. Therefore, to understand their role in tumor invasion, it is...

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Identifiers

PMID: 15623598
DOI: 10.1158/1078-0432.CCR-04-0424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.PMID 15623598Read ↗

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