Article
Hematopoietic alterations after exposure to T-2 mycotoxin.
Toxicon : official journal of the International Society on Toxinology - 1 Sept 1994
Smith B J, Holladay S D, Blaylock B L
Abstract excerpt
Adult mice were exposed by oral gavage to 0.75, 1.25, or 1.75 mg/kg body weight T-2 mycotoxin for 5 consecutive days. Thymic atrophy on the 2nd day following cessation of dosing was profound, and was characterized by significant decreases in the total number of cells within all phenotypes defined by CD4 and CD8 cell-surface antigen expression. Further, the distribution of thymocytes within these phenotypes was...
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