Article
Hematopoietic alterations after exposure to T-2 mycotoxin.
Toxicon : official journal of the International Society on Toxinology - 1 Sept 1994
Smith B J, Holladay S D, Blaylock B L
Abstract excerpt
Adult mice were exposed by oral gavage to 0.75, 1.25, or 1.75 mg/kg body weight T-2 mycotoxin for 5 consecutive days. Thymic atrophy on the 2nd day following cessation of dosing was profound, and was characterized by significant decreases in the total number of cells within all phenotypes defined...
Topics
- Administration, Oral
- Animals
- Antigens, Surface
- Atrophy
- Bone Marrow
- Bone Marrow Cells
- CD4-CD8 Ratio
- Cell Division
- Female
- Flow Cytometry
- Gene Expression Regulation
- Hematopoiesis
- Immunosuppression Therapy
- Mice
- Phenotype
- Random Allocation
- Spleen
- T-2 Toxin