Analysis of genetic diversity in cytotoxin-producing and non-cytotoxin-producing Helicobacter pylori strains.

doi:10.1093/infdis/172.1.290

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Article

Analysis of genetic diversity in cytotoxin-producing and non-cytotoxin-producing Helicobacter pylori strains.

The Journal of infectious diseases - 1 Jul 1995

Garner J A, Cover T L

Abstract excerpt

Analysis of 32 Helicobacter pylori strains indicated a strong association between the presence of the cagA gene and a specific type of vacA allele found predominantly in cytotoxin-producing strains (P < .001). To determine whether tox+/CagA+ and tox-/CagA- strains constituted two separate noncomb...

Topics

Base Sequence
Cytotoxins
DNA Primers
Genes, Bacterial
Genetic Variation
HeLa Cells
Helicobacter pylori
Humans
Introns
Molecular Sequence Data
Polymerase Chain Reaction
Restriction Mapping
Sequence Homology, Nucleic Acid
Species Specificity

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