A pre-start checkpoint preventing mitosis in fission yeast acts independently of p34cdc2 tyrosine phosphorylation.

doi:10.1002/j.1460-2075.1995.tb07276.x

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Article

A pre-start checkpoint preventing mitosis in fission yeast acts independently of p34cdc2 tyrosine phosphorylation.

The EMBO journal - 15 Jun 1995

Hayles J, Nurse P

Abstract excerpt

We have monitored the tyrosine (Y15) phosphorylated and dephosphorylated forms of p34cdc2 from Schizosaccharomyces pombe as cells proceed through the cell cycle. Y15 is dephosphorylated in G1 before start and becomes phosphorylated only after cells pass start and enter late G1. This transition is...

Topics

Antibodies, Fungal
Antibody Specificity
CDC2 Protein Kinase
Cell Fractionation
Cyclin B
Cyclins
Fungal Proteins
G1 Phase
Mitosis
Mutation
Phosphorylation
Schizosaccharomyces
Solubility
Temperature
Tyrosine

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