The fission yeast cdc18+ gene product couples S phase to START and mitosis.

doi:10.1016/0092-8674(93)90427-r

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Article

The fission yeast cdc18+ gene product couples S phase to START and mitosis.

Cell - 30 Jul 1993

Kelly T J, Martin G S, Forsburg S L, Stephen R J, Russo A, Nurse P

Abstract excerpt

Commitment to the cell cycle in fission yeast requires the function of the cdc10+ transcriptional activator at START. The product of the cdc18+ gene is a major downstream target of cdc10+, and transcription of cdc18+ is activated by cdc10+ during passage through START. The cdc18+ function is required for entry into S phase. In addition, the product of the cdc18+ gene is part of the checkpoint control that...

Topics

Amino Acid Sequence
Base Sequence
Cell Cycle
Cell Cycle Proteins
Cloning, Molecular
Fungal Proteins
Gene Deletion
Genes, Fungal
Mitosis
Models, Genetic
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Periodicity

Phenotype

S Phase

Schizosaccharomyces

Schizosaccharomyces pombe Proteins

Sequence Homology, Amino Acid

Suppression, Genetic

Source

Open in PubMed

Identifiers

PMID: 7916658
DOI: 10.1016/0092-8674(93)90427-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7916658-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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