Article
Full activation of p34CDC28 histone H1 kinase activity is unable to promote entry into mitosis in checkpoint-arrested cells of the yeast Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Jun 1993
Stueland C S, Lew D J, Cismowski M J, Reed S I
Abstract excerpt
In most cells, mitosis is dependent upon completion of DNA replication. The feedback mechanisms that prevent entry into mitosis by cells with damaged or incompletely replicated DNA have been termed checkpoint controls. Studies with the fission yeast Schizosaccharomyces pombe and Xenopus egg extra...
Topics
- CDC28 Protein Kinase, S cerevisiae
- Enzyme Activation
- Fluorescent Antibody Technique
- Genes, Fungal
- Genotype
- Hydroxyurea
- Mitosis
- Protamine Kinase
- Protein Kinases
- Saccharomyces cerevisiae