Article
T-cell Activation Induces Dynamic Changes in miRNA Expression Patterns in CD4 and CD8 T-cell Subsets.
MicroRNA (Shariqah, United Arab Emirates) - 1 Jan 2015
Teteloshvili Nato, Smigielska-Czepiel Katarzyna, Kroesen Bart-Jan, Brouwer Elisabeth, Kluiver Joost, Boots Annemieke M H, van den Berg Anke
Abstract excerpt
T-cell activation affects microRNA (miRNA) expression in T-cell subsets. However, little is known about the kinetics of miRNA regulation and possible differences between CD4 and CD8 T cells. In this study we set out to analyze the kinetics of activation-induced expression regulation of twelve pre-selected miRNAs. The dynamics of the expression of these miRNAs was studied in sorted CD4 and CD8 CD45RO- T cells of...
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