Article
Hemodialysis affects phenotype and proliferation of CD4-positive T lymphocytes.
Journal of clinical immunology - 1 Feb 2012
Lisowska Katarzyna A, Dębska-Ślizień Alicja, Jasiulewicz Aleksandra, Heleniak Zbigniew, Bryl Ewa, Witkowski Jacek M
Abstract excerpt
CD4(+) T lymphocytes of patients with chronic kidney disease (CKD) are characterized by reduced levels of crucial surface antigens and changes in the cell cycle parameters. Recombinant human erythropoietin (rhEPO) normalizes their altered phenotype and proliferative capacity. Mechanisms leading to the deficient responses of T lymphocytes are still not clear but it is postulated that immunological changes are...
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