Stimulation of DNA synthesis by mouse DNA helicase B in a DNA replication system containing eukaryotic replication origins.

doi:10.1021/bi00024a016

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Article

Stimulation of DNA synthesis by mouse DNA helicase B in a DNA replication system containing eukaryotic replication origins.

Biochemistry - 20 Jun 1995

Matsumoto K, Seki M, Masutani C, Tada S, Enomoto T, Ishimi Y

Abstract excerpt

A number of DNA helicases have been isolated from mammalian cells, but their abilities to stimulate DNA replication accompanied with DNA unwinding have not been addressed so far. We constructed a model DNA replication system using the yeast autonomously replicating sequence (ARS) as the replication origin. In this system, SV40 T antigen as a DNA helicase assembles to the replication origin where the DNA duplex is...

Topics

Adenosine Triphosphatases
Animals
Antigens, Viral, Tumor
Base Sequence
DNA Helicases
DNA Polymerase II
DNA Primase
DNA Replication
DNA Topoisomerases, Type II
DNA, Fungal
DNA, Superhelical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

DNA-Binding Proteins

Eukaryotic Cells

Genes, myc

Mice

Models, Genetic

Molecular Sequence Data

Mutation

Source

Open in PubMed

Identifiers

PMID: 7794903
DOI: 10.1021/bi00024a016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7794903-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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