Article
A DNA replication enhancer in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1990
Walker S S, Francesconi S C, Eisenberg S
Abstract excerpt
We have dissected the autonomously replicating sequence ARS121 using site-directed in vitro mutagenesis. Three domains important for origin function were identified; one of these is essential and contains an 11-base-pair sequence resembling the canonical ARS core consensus; the second region, deletion of which affects the efficiency of the origin, is located 3' to the T-rich strand of the essential sequence and...
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