Mediation of PACAP-like neuropeptide transmission by coactivation of Ras/Raf and cAMP signal transduction pathways in Drosophila.

doi:10.1038/375588a0

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Article

Mediation of PACAP-like neuropeptide transmission by coactivation of Ras/Raf and cAMP signal transduction pathways in Drosophila.

Nature - 15 Jun 1995

Zhong Y

Abstract excerpt

Much work on the signal transduction mechanisms underlying neurotransmission has been directed towards studying the roles of the cyclic AMP and phosphoinositide pathways. Upon ligand binding, the transmitter receptors interact with heterotrimeric G proteins, allowing G alpha and G beta gamma subu...

Topics

Adenylyl Cyclases
Animals
Cyclic AMP
Drosophila
GTP-Binding Proteins
Mutation
Neuropeptides
Pituitary Adenylate Cyclase-Activating Polypeptide
Potassium
Protein Serine-Threonine Kinases
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-raf
Signal Transduction
ras Proteins

Source

Open in PubMed

Identifiers

PMID: 7791875
DOI: 10.1038/375588a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7791875-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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