Neuronally expressed Ras-family GTPase Di-Ras modulates synaptic activity in Caenorhabditis elegans.

doi:10.1111/j.1365-2443.2012.01627.x

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Article

Neuronally expressed Ras-family GTPase Di-Ras modulates synaptic activity in Caenorhabditis elegans.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Sept 2012

Tada Minoru, Gengyo-Ando Keiko, Kobayashi Tetsuo, Fukuyama Masamitsu, Mitani Shohei, Kontani Kenji, Katada Toshiaki

Abstract excerpt

Ras-family GTPases regulate a wide variety of cellular functions including cell growth and differentiation. Di-Ras, which belongs to a distinct subfamily of Ras-family GTPases, is expressed predominantly in brain, but the role of Di-Ras in nervous systems remains totally unknown. Here, we report that the Caenorhabditis elegans Di-Ras homologue drn-1 is expressed specifically in neuronal cells and involved in...

Topics

Acetylcholine
Aldicarb
Amino Acid Sequence
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cholinergic Neurons
Cholinesterase Inhibitors
Drug Resistance
GTP Phosphohydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

GTP-Binding Protein alpha Subunits, Gi-Go

Guanine Nucleotide Exchange Factors

Immunoprecipitation

Neuromuscular Junction

Phenotype

Protein Interaction Mapping

Sequence Deletion

Synaptic Transmission

Source

Open in PubMed

Identifiers

PMID: 22897658
DOI: 10.1111/j.1365-2443.2012.01627.x

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