Article
In vivo functional analysis of Drosophila Gap1: involvement of Ca2+ and IP4 regulation.
Mechanisms of development - 1 Mar 1999
Powe A C, Strathdee D, Cutforth T, D'Souza-Correia T, Gaines P, Thackeray J, Carlson J, Gaul U
Abstract excerpt
Control of Ras activity is crucial for normal cellular behavior such as fate determination during development. Although several GTPase activating proteins (GAPs) have been shown to act as negative regulators of Ras, the mechanisms involved in regulating their activity in vivo are poorly understood. Here we report the structural requirements for Gap1 activity in cone cell fate decisions during Drosophila eye...
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