Article
Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase.
Molecular and cellular biology - 1 Jul 1995
Nathan D F, Lindquist S
Abstract excerpt
Hsp90 is a protein chaperone whose functions are focused on a specific set of target proteins. The nature of Hsp90's interactions with these proteins is poorly understood. To provide tools for examining these interactions, we have isolated eight broadly distributed temperature-sensitive (ts) poin...
Topics
- DNA Mutational Analysis
- HSP90 Heat-Shock Proteins
- Heat-Shock Proteins
- Hot Temperature
- Oncogene Protein pp60(v-src)
- Phenotype
- Point Mutation
- Protein Binding
- Receptors, Glucocorticoid
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins