Article
A role for Hsp90 in retinoid receptor signal transduction.
Molecular biology of the cell - 1 Dec 1995
Holley S J, Yamamoto K R
Abstract excerpt
The ubiquitous heat shock protein Hsp90 appears to participate directly in the function of a broad range of cellular signal transduction components, including steroid hormone receptors; however, an evolutionarily related subclass of intracellular receptors, exemplified by the retinoid receptors RAR and RXR, had been inferred from biochemical studies to function independently of Hsp90. To examine this issue...
Topics
- Animals
- Base Sequence
- Chickens
- Cloning, Molecular
- Desoxycorticosterone
- Genotype
- HSP90 Heat-Shock Proteins
- Humans
- Mammals
- Molecular Sequence Data
- Mutagenesis, Insertional
- Oligodeoxyribonucleotides
- Plasmids
- Promoter Regions, Genetic
- Receptors, Retinoic Acid
- Recombinant Proteins
- Retinoid X Receptors
- Saccharomyces cerevisiae
