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Article

The nerve growth factor-responsive PC12 cell line does not express the Myc dimerization partner Max.

Molecular and cellular biology - 1 Jul 1995

Hopewell R, Ziff E B

Abstract excerpt

Heterodimerization of Max with the nuclear oncoprotein Myc and the differentiation-associated proteins Mad and Mxi1 enables these factors to bind E-box sites in DNA and control genes implicated in cell proliferation and differentiation. We show that in the PC12 pheochromocytoma tumor cell line, functional Max protein is not expressed because of the synthesis of a mutant max transcript. This transcript encodes a...

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Identifiers

PMID: 7791753
DOI: 10.1128/MCB.15.7.3470
PMCID: PMC230583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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