Article
The nerve growth factor-responsive PC12 cell line does not express the Myc dimerization partner Max.
Molecular and cellular biology - 1 Jul 1995
Hopewell R, Ziff E B
Abstract excerpt
Heterodimerization of Max with the nuclear oncoprotein Myc and the differentiation-associated proteins Mad and Mxi1 enables these factors to bind E-box sites in DNA and control genes implicated in cell proliferation and differentiation. We show that in the PC12 pheochromocytoma tumor cell line, f...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Basic-Leucine Zipper Transcription Factors
- Cell Division
- Chromosome Aberrations
- Cloning, Molecular
- DNA, Complementary
- DNA-Binding Proteins
- Molecular Sequence Data
- Mutation
- Nerve Growth Factors
- PC12 Cells
- Protein Binding
- Protein Conformation
- Proto-Oncogene Proteins c-myc
- RNA Processing, Post-Transcriptional