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Article

Interleukin 6 is essential for in vivo development of B lineage neoplasms.

The Journal of experimental medicine - 1 Jul 1995

Hilbert D M, Kopf M, Mock B A, Köhler G, Rudikoff S

Abstract excerpt

Interleukin (IL) 6 has been suggested to be the major cytokine responsible for proliferation of neoplastic plasma cells in both human myeloma and mouse plasmacytoma. Much of the evidence supporting this suggestion is derived from in vitro studies in which the survival or proliferation of some plasma cell tumors has been found to be IL-6 dependent. However, it remains unclear whether this dependency is the...

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Identifiers

PMID: 7790819
DOI: 10.1084/jem.182.1.243
PMCID: PMC2192088

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Interleukin 6 is essential for in vivo development of B lineage neoplasms.PMID 7790819Read ↗

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