Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retention and multilineage expression of human hematopoietic stem cells in human‐sheep chimeras

1 Jan 1995

Abstract excerpt

We have taken advantage of the permissive environment of the early gestational age fetus to engraft human hematopoietic stem cells (HSC) into preimmune fetal lambs. The resulting chimeras exhibit long-term multilineage engraftment of human cells in the bone marrow (BM) and peripheral blood (PB). Long-term multilineage reconstitution of second generation recipients by human cells isolated from chimeric sheep BM...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Mesenchymal stem cell research
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7787777
DOI: 10.1002/stem.5530130202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retention and multilineage expression of human hematopoietic stem cells in human‐sheep chimerasPMID 7787777Read ↗

Long-term repopulating ability of xenogeneic transplanted human fetal liver hematopoietic stem cells in sheep.Semantic proximity Read ↗

A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates.Semantic proximity Read ↗

Formation of human hepatocytes by human hematopoietic stem cells in sheep.Semantic proximity Read ↗

Improvement of multilineage hematopoiesis in hematopoietic stem cell-transferred c-kit mutant NOG-EXL humanized mice.Semantic proximity Read ↗

Human Mesenchymal Stem Cells Form Purkinje Fibers in Fetal Sheep HeartSemantic proximity Read ↗

Stable long-term mixed chimerism achieved in a canine model of allogeneic in utero hematopoietic cell transplantationSemantic proximity Read ↗

Tissue-specific engraftment after in utero transplantation of allogeneic mesenchymal stem cells into sheep fetusesSemantic proximity Read ↗

The human/sheep xenograft model: a large animal model of human hematopoiesis.Semantic proximity Read ↗

A long-term culture system for the expansion of hematopoietic stem cells from embryonic yolk sac with the capacity to seed erythroid and lymphoid development in vitro and to reconstitute the lymphoid compartment in severe combined immunodeficient mice.Semantic proximity Read ↗

The time course of engraftment of human mesenchymal stem cells in fetal heart demonstrates that Purkinje fiber aggregates derive from a single cell and not multi-cell homing.Semantic proximity Read ↗

Human T cells in the SCID-hu mouse are phenotypically normal and functionally competent.Semantic proximity Read ↗

Conserved and divergent aspects of human T-cell development and migration in humanized mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.