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Article

Testing for segregation distortion in the HLA complex.

Biometrics - 1 Dec 1994

Jin K, Speed T P, Klitz W, Thomson G

Abstract excerpt

One of the long-standing issues in HLA research is whether there is segregation distortion in the HLA complex in human populations. In this paper we study some simple statistical models aimed at detecting segregation distortion. We present a statistic to test the Mendelian null hypothesis of equal transmission probabilities. To assess the possible contribution of multiple alleles to segregation distortion, we...

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PMID: 7787001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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