Article
Measuring the relative information in allele-sharing linkage studies.
Biometrics - 1 Jun 2004
Nicolae Dan L, Kong Augustine
Abstract excerpt
In the context of allele-sharing methods, this article investigates ways of measuring the information in the marker data relative to the amount of information that would have been available if the identity-by-descent (IBD) process were known. Such measures are needed to decide whether new markers can substantially modify the evidence for excess sharing. We propose new measures that take advantage of the...
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