Article
Tests of random mating for a highly polymorphic locus: application to HLA data.
Biometrics - 1 Sept 1995
Jin K, Speed T P, Thomson G
Abstract excerpt
Testing for random mating at an HLA locus is a difficult problem because of the highly polymorphic nature of the HLA loci. We discuss some methodological issues and propose several tests. A simulation study is conducted to evaluate these tests. The single allele test and the shared allele test deal with small sample sizes by aggregating the data in different ways. The shared allele test is found to be a more...
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