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Article

Hardy-Weinberg testing for HLA class II (DRB1, DQA1, DQB1, and DPB1) loci in 26 human ethnic groups.

Tissue antigens - 1 Dec 1999

Chen J J, Hollenbach J A, Trachtenberg E A, Just J J, Carrington M, Rønningen K S, Begovich A, King M C, McWeeney S, Mack S J, Erlich H A, Thomson G

Abstract excerpt

Testing the fit of population data to Hardy-Weinberg proportions is crucial in the validation of many current approaches in population genetic studies. In this paper, we tested fit to Hardy-Weinberg proportions using exact approaches for both the overall and individual heterozygote genotype data of four HLA Class II loci: DRB1, DQA1, DQB1, and DPB1, from 26 human populations. Eighty of 99 overall tests fit the...

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Identifiers

PMID: 10674966
DOI: 10.1034/j.1399-0039.1999.540601.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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