SENCA: A Multilayered Codon Model to Study the Origins and Dynamics of Codon Usage.

doi:10.1093/gbe/evw165

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Article

SENCA: A Multilayered Codon Model to Study the Origins and Dynamics of Codon Usage.

Genome biology and evolution - 25 Aug 2016

Pouyet Fanny, Bailly-Bechet Marc, Mouchiroud Dominique, Guéguen Laurent

Abstract excerpt

Gene sequences are the target of evolution operating at different levels, including the nucleotide, codon, and amino acid levels. Disentangling the impact of those different levels on gene sequences requires developing a probabilistic model with three layers. Here we present SENCA (site evolution...

Topics

Amino Acid Sequence
Amino Acid Substitution
Codon
Evolution, Molecular
Humans
Models, Genetic
Models, Statistical
Mutation
Nucleotides
Selection, Genetic

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