Article
Regulation of neurotransmitter release by synapsin III.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 2002
Feng Jian, Chi Ping, Blanpied Thomas A, Xu Yimei, Magarinos Ana Maria, Ferreira Adriana, Takahashi Reisuke H, Kao Hung-Teh, McEwen Bruce S, Ryan Timothy A, Augustine George J, Greengard Paul
Abstract excerpt
Synapsin III is the most recently identified member of the synapsin family, a group of synaptic vesicle proteins that play essential roles in neurotransmitter release and neurite outgrowth. Here, through the generation and analysis of synapsin III knock-out mice, we demonstrate that synapsin III regulates neurotransmitter release in a manner that is distinct from that of synapsin I or synapsin II. In mice lacking...
Topics
- Action Potentials
- Animals
- Axons
- Brain
- Cells, Cultured
- Electric Stimulation
- Endocytosis
- Excitatory Postsynaptic Potentials
- Fluorescent Dyes
- Gene Targeting