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Article

Acetylation of lysine 40 in alpha-tubulin is not essential in Tetrahymena thermophila.

The Journal of cell biology - 1 Jun 1995

Gaertig J, Cruz M A, Bowen J, Gu L, Pennock D G, Gorovsky M A

Abstract excerpt

In Tetrahymena, at least 17 distinct microtubule structures are assembled from a single primary sequence type of alpha- and beta-tubulin heterodimer, precluding distinctions among microtubular systems based on tubulin primary sequence isotypes. Tetrahymena tubulins also are modified by several types of posttranslational reactions including acetylation of alpha-tubulin at lysine 40, a modification found in most...

Topics

Acetylation
Animals
Gene Transfer Techniques
Lysine
Microtubules
Mutation
Protein Processing, Post-Translational
Tetrahymena
Tubulin

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7775576
DOI: 10.1083/jcb.129.5.1301
PMCID: PMC2120470

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7775576-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Acetylation of lysine 40 in alpha-tubulin is not essential in Tetrahymena thermophila.PMID 7775576Read ↗

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αTAT1 is the major α-tubulin acetyltransferase in mice.Semantic proximity Read ↗

Both carboxy-terminal tails of alpha- and beta-tubulin are essential, but either one will suffice.Semantic proximity Read ↗

Mutating different α-tubulin acetylation sites has distinct effects on axon terminal morphogenesis in Drosophila melanogaster.Semantic proximity Read ↗

Effects of mutating α-tubulin lysine 40 on sensory dendrite development.Semantic proximity Read ↗

⍺TAT1-dependent microtubule acetylation is required for touch sensation in zebrafish but not for cilia-driven morphogenesis.Semantic proximity Read ↗

Mutations of tubulin glycylation sites reveal cross-talk between the C termini of alpha- and beta-tubulin and affect the ciliary matrix in Tetrahymena.Semantic proximity Read ↗

α-Tubulin mutations alter oryzalin affinity and microtubule assembly properties to confer dinitroaniline resistance.Semantic proximity Read ↗

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Tetrahymena thermophila contains a conventional gamma-tubulin that is differentially required for the maintenance of different microtubule-organizing centers.Semantic proximity Read ↗

TgATAT-Mediated α-Tubulin Acetylation Is Required for Division of the Protozoan Parasite Toxoplasma gondiiSemantic proximity Read ↗

Post-translational modifications and multiple tubulin isoforms in Nicotiana tabacum L. cells.Semantic proximity Read ↗

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