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Article

α-Tubulin mutations alter oryzalin affinity and microtubule assembly properties to confer dinitroaniline resistance.

Eukaryotic cell - 1 Dec 2010

Lyons-Abbott Sally, Sackett Dan L, Wloga Dorota, Gaertig Jacek, Morgan Rachel E, Werbovetz Karl A, Morrissette Naomi S

Abstract excerpt

Plant and protozoan microtubules are selectively sensitive to dinitroanilines, which do not disrupt vertebrate or fungal microtubules. Tetrahymena thermophila is an abundant source of dinitroaniline-sensitive tubulin, and we have modified the single T. thermophila α-tubulin gene to create strains...

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Identifiers

PMID: 20870876
DOI: 10.1128/EC.00140-10
PMCID: PMC3008275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20870876-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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