Mutating different α-tubulin acetylation sites has distinct effects on axon terminal morphogenesis in Drosophila melanogaster.

Abstract excerpt

Microtubules are created from uniform α- and β-tubulin building blocks but typically carry out a variety of specialized functions within a cell. The post-translational modification of tubulin is one means by which microtubule function can be tuned to match different cellular activities. While multiple sites of acetylation have been identified in tubulin, particularly α-tubulin, the effect(s) of acetylation at...

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