Article
Mutational analysis of the J-K stem-loop region of the encephalomyocarditis virus IRES.
Journal of virology - 1 Jul 1995
Hoffman M A, Palmenberg A C
Abstract excerpt
Cap-independent translation of encephalomyocarditis virus (EMCV) RNA is controlled by a segment of the 5' untranslated region termed the internal ribosomal entry site, or IRES. The IRES contains a series of stem-loop structural elements. The J and K stems (EMCV bases 682 to 795), near the center of the IRES, are well conserved among all cardio-, aphtho-, and hepatoviruses. We have examined the biological roles of...
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