Molecular cloning of a gene, DHS1, which complements a drug-hypersensitive mutation of the yeast Saccharomyces cerevisiae.

doi:10.1271/bbb.58.391

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Article

Molecular cloning of a gene, DHS1, which complements a drug-hypersensitive mutation of the yeast Saccharomyces cerevisiae.

Bioscience, biotechnology, and biochemistry - 1 Feb 1994

Lee Y S, Shimizu J, Yoda K, Yamasaki M

Abstract excerpt

We isolated a Saccharomyces cerevisiae mutant, CH108, which shows hypersensitivity to cycloheximide, bleomycin, actinomycin D, 5-fluorouracil, and several other antibiotics. The mutant cells showed irregular shapes with swelling and were also hypersensitive to Zymolyase digestion. The mutant cell...

Topics

Amino Acid Sequence
Base Sequence
Cell Membrane
Cloning, Molecular
Drug Hypersensitivity
Genes, Fungal
Molecular Sequence Data
Mutagenesis
Mutation
Phenotype
Saccharomyces cerevisiae

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