Article
AUR1, a novel gene conferring aureobasidin resistance on Saccharomyces cerevisiae: a study of defective morphologies in Aur1p-depleted cells.
Molecular & general genetics : MGG - 23 May 1996
Hashida-Okado T, Ogawa A, Endo M, Yasumoto R, Takesako K, Kato I
Abstract excerpt
Aureobasidin A (AbA), a cyclic depsipeptide produced by Aureobasidium pullulans R106, is highly toxic to fungi including Saccharomyces cerevisiae. We isolated several dominant mutants of S. cerevisiae which are resistant to more than 25 micrograms/ml of AbA. From a genomic library of one such AUR1 mutant, the AUR1R (for aureobasidin resistant) mutant gene was isolated as a gene that confers resistance to AbA on...
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