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Article

A novel yeast gene, RHK1, is involved in the synthesis of the cell wall receptor for the HM-1 killer toxin that inhibits beta-1,3-glucan synthesis.

Molecular & general genetics : MGG - 26 Mar 1997

Kimura T, Kitamoto N, Kito Y, Iimura Y, Shirai T, Komiyama T, Furuichi Y, Sakka K, Ohmiya K

Abstract excerpt

The HM-1 killer toxin from Hansenula mrakii is known to inhibit cell wall beta-1,3-glucan synthase of Saccharomyces cerevisiae and other sensitive strains of yeast. A number of mutants of Saccharomyces cerevisiae that show resistance to this toxin were isolated in order to clarify the killing mechanism of the toxin. These mutants, designated rhk (resistant to Hansenula killer), were classified into three...

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PMID: 9108275
DOI: 10.1007/s004380050401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel yeast gene, RHK1, is involved in the synthesis of the cell wall receptor for the HM-1 killer toxin that inhibits beta-1,3-glucan synthesis.PMID 9108275Read ↗

HKR1 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

N-glycosylation is involved in the sensitivity of Saccharomyces cerevisiae to HM-1 killer toxin secreted from Hansenula mrakii IFO 0895.Semantic proximity Read ↗

Involvement of cell wall beta-glucan in the action of HM-1 killer toxin.Semantic proximity Read ↗

A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin.Semantic proximity Read ↗

Killer-toxin-resistant kre12 mutants of Saccharomyces cerevisiae: genetic and biochemical evidence for a secondary K1 membrane receptor.Semantic proximity Read ↗

Expression of K1 Toxin Derivatives in Saccharomyces cerevisiae Mimics Treatment with Exogenous Toxin and Provides a Useful Tool for Elucidating K1 Mechanisms of Action and Immunity.Semantic proximity Read ↗

The KNH1 gene of Saccharomyces cerevisiae is a functional homolog of KRE9.Semantic proximity Read ↗

Isolation and characterization of Saccharomyces cerevisiae mutants with a different degree of resistance to killer toxins K1 and K2.Semantic proximity Read ↗

A mutational analysis of killer toxin resistance in Saccharomyces cerevisiae identifies new genes involved in cell wall (1-->6)-beta-glucan synthesis.Semantic proximity Read ↗

Genetic and molecular approaches to synthesis and action of the yeast killer toxin.Semantic proximity Read ↗

P-type ATPase spf1 mutants show a novel resistance mechanism for the killer toxin SMKT.Semantic proximity Read ↗

Isolation of Candida glabrata homologs of the Saccharomyces cerevisiae KRE9 and KNH1 genes and their involvement in cell wall beta-1,6-glucan synthesis.Semantic proximity Read ↗

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