Article
Kinetics of rapid RNA evolution in vitro.
Journal of molecular evolution - 1 Oct 1991
Davis B K
Abstract excerpt
A rapidly acquired partial resistance to the replicase antagonist, ethidium bromide (EB), seen by Spiegelman and coresearchers in Q beta RNA variants competitively replicating under defined conditions in vitro, reflected existence of a pool of mutant RNA molecules, preadapted to EB, and their cro...
Topics
- Biological Evolution
- Drug Resistance
- Ethidium
- Genetic Variation
- Kinetics
- Mathematics
- RNA
- RNA-Dependent RNA Polymerase
