Article
Genetic susceptibility to multiple sclerosis.
Annals of neurology - 1 Dec 1994
Haegert D G, Marrosu M G
Abstract excerpt
Twin studies have established that susceptibility to multiple sclerosis (MS) is partly genetic. Attempts to identify the relevant genetic loci have involved population-based studies, to detect associations between a genetic marker and MS, and family studies, to detect linkage between a putative marker and MS. Most of this genetic work is driven by the view that MS is an autoimmune disease. Thus, the focus has...
Topics
- Genetic Predisposition to Disease
- HLA Antigens
- Humans
- Multiple Sclerosis
- Polymorphism, Genetic
- Receptors, Antigen, T-Cell
- Twin Studies as Topic