Article
An attenuated vaccine for AIDS?
Lancet (London, England) - 27 May 1995
Beale J
Abstract excerpt
One of the few bright prospects in AIDS research is the findings from a study of an attenuated SIV vaccine in monkeys. The vaccine consists of SIV with the nef region deleted (SIVmac239). All 6 monkeys vaccinated with the nef-deleted virus were still healthy and alive 5 years after vaccination, while 11 of the 12 rhesus monkeys administered the virulent SIVmac died. The case monkeys were challenged with virulent...
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