Article
Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 May 1995
Joly C, Gomeza J, Brabet I, Curry K, Bockaert J, Pin J P
Abstract excerpt
The main excitatory neurotransmitter in the brain, glutamate (Glu), activates not only receptor-channels, but also receptors coupled to G-protein called metabotropic Glu receptors (mGluRs). Eight genes coding for mGluRs have been characterized to date giving rise to even more proteins due to alte...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Brain
- Cell Line
- Cyclic AMP
- Cycloleucine
- DNA Primers
- Female
- Gene Library
- Genetic Variation
- Glutamic Acid
- Ibotenic Acid
- In Situ Hybridization