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Article

G protein mutations in pituitary tumors: a study on Turkish patients.

Pituitary - 1 Sept 2003

Kan Beki, Esapa Christopher, Sipahi Tammam, Nacar Cevdet, Ozer Fahir, Sayhan Nur Buyru, Kaynar Mehmet Yaşar, Sarioğlu Ali Cetin, Harris Philip Edward

Abstract excerpt

Activating mutations of the G proteins, Gsalpha (gsp) and Gi2alpha (gip) have been reported in subsets of pituitary tumors. The objective of the study was to assess the frequency of gsp and gip mutations in pituitary tumors from Turkish patients and to investigate the possibility of mutations of protein kinase A catalytic subunit (PKAC) that activates the downstream effectors of adenylyl cyclase. PCR-amplified...

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Identifiers

PMID: 14703016
DOI: 10.1023/b:pitu.0000004797.89592.5e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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