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Article

G‐protein mutations in human pituitary adrenocorticotrophic hormone‐secreting adenomas

1 Feb 1995

Abstract excerpt

Activating mutations of Gs alpha (gsp) and Gi2 alpha (gip) have been described in various endocrine neoplastic conditions. The objective of this study was to assess the prevalence of gsp and gip mutations in human adrenocorticotrophin hormone-secreting pituitary adenomas. Adrenocorticotrophin hormone production and secretion by pituitary corticotroph cells is under stimulatory control by corticotrophin-releasing...

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Identifiers

PMID: 7737262
DOI: 10.1111/j.1365-2362.1995.tb01537.x

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