Article
Relation of coronary atherosclerosis and apolipoprotein E genotypes in Alzheimer patients.
Stroke - 1 May 1995
Kosunen O, Talasniemi S, Lehtovirta M, Heinonen O, Helisalmi S, Mannermaa A, Paljärvi L, Ryynänen M, Riekkinen P J, Soininen H
Abstract excerpt
BACKGROUND AND PURPOSE: Apolipoprotein E (apoE) epsilon 4 allele has been associated with a high risk for coronary heart disease. Increased frequency of the epsilon 4 allele has also been reported in patients with late-onset familial and sporadic Alzheimer's disease (AD). The aim of this study was to investigate the degree of coronary and cerebral atherosclerosis in a neuropathologically verified series of AD...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Amyloid
- Apolipoproteins E
- Autopsy
- Brain
- Coronary Artery Disease
- Coronary Vessels
- Female