Article
Relation between butyrylcholinesterase K variant, paraoxonase 1 (PON1) Q and R and apolipoprotein E epsilon 4 genes in early-onset coronary artery disease.
Clinical biochemistry - 1 May 2002
Nassar Bassam A, Darvesh Sultan, Bevin Lisa D, Rockwood Kenneth, Kirkland Susan A, O'Neill Blair J, Bata Iqbal R, Johnstone David E, Title Lawrence M
Abstract excerpt
OBJECTIVES: The common K variant of butyrylcholinesterase (BChE-K), an enzyme which metabolizes acetylcholine and organophosphates, has been associated with Alzheimer's disease, especially in the presence of the apolipoprotein E epsilon 4 allele (APOE-epsilon 4). Although APOE-epsilon 4 has been associated with the development of coronary artery disease (CAD), an association between the BChE-K variant and CAD has...
Topics
- Age of Onset
- Aged
- Alleles
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Aryldialkylphosphatase
- Butyrylcholinesterase
- Coronary Artery Disease
- Esterases
- Female
- Heterozygote
- Humans