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Article

A nucleolin-binding 3' untranslated region element stabilizes beta-globin mRNA in vivo.

Molecular and cellular biology - 1 Mar 2006

Jiang Yong, Xu Xiang-Sheng, Russell J Eric

Abstract excerpt

The normal expression of human beta globin is critically dependent upon the constitutively high stability of its encoding mRNA. Unlike with alpha-globin mRNA, the specific cis-acting determinants and trans-acting factors that participate in stabilizing beta-globin mRNA are poorly described. The current work uses a linker-scanning strategy to identify a previously unknown determinant of mRNA stability within the...

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Identifiers

PMID: 16508016
DOI: 10.1128/MCB.26.6.2419-2429.2006
PMCID: PMC1430272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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