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Article

AUF-1 and YB-1 are critical determinants of β-globin mRNA expression in erythroid cells.

Blood - 26 Jan 2012

van Zalen Sebastiaan, Jeschke Grace R, Hexner Elizabeth O, Russell J Eric

Abstract excerpt

The normal accumulation of β-globin protein in terminally differentiating erythroid cells is critically dependent on the high stability of its encoding mRNA. The molecular basis for this property, though, is incompletely understood. Factors that regulate β-globin mRNA within the nucleus of early erythroid progenitors are unlikely to account for the constitutively high half-life of β-globin mRNA in the cytoplasm...

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Identifiers

PMID: 22134169
DOI: 10.1182/blood-2011-10-387316
PMCID: PMC3271717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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