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Article

Different Voltage-dependent Inhibition by Dihydropyridines of Human Ca2+ Channel Splice Variants

1 May 1995

Abstract excerpt

Voltage-dependent inhibition by 1,4-dihydropyridines is a characteristic property of L-type Ca2+ channels. Six out of 50 exons of the channel alpha 1C subunit gene are subjected to alternative splicing, thus generating channel isoform diversity. Using Xenopus oocytes as an expression system, we have found that transmembrane segment IIIS2 of human alpha 1C subunit is involved in the control of voltage dependence...

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PMID: 7737988
DOI: 10.1074/jbc.270.18.10540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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