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Article

The impact of splice isoforms on voltage-gated calcium channel alpha1 subunits.

The Journal of physiology - 1 Feb 2004

Jurkat-Rott Karin, Lehmann-Horn Frank

Abstract excerpt

Semi-conserved exon boundaries in members of the CACNA1 gene family result in recurring pre-mRNA splicing patterns. The resulting variations in the encoded pore-forming subunit of the voltage-gated calcium channel affect functionally significant regions, such as the vicinity of the voltage-sensing S4 segments or the intracellular loops that are important for protein interaction. In addition to generating...

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Identifiers

PMID: 14645450
DOI: 10.1113/jphysiol.2003.052712
PMCID: PMC1664792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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