Ca(V)2.1 P/Q-type calcium channel alternative splicing affects the functional impact of familial hemiplegic migraine mutations: implications for calcium channelopathies.

Abstract excerpt

Alternative splicing is known to generate multiple functionally distinct calcium channel variants that exhibit unique spatial and temporal expression patterns. In humans, naturally occurring mutations in genes encoding calcium channel pore forming alpha(1)-subunits are associated with several sev...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Action Potentials
• Share to Alternative Splicing
• Share to Calcium Channels, N-Type